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Postgraduate Admissions

About the Cambridge Institute for Medical Research

The recent explosion of genomics has led to a rapid increase in data describing the genetic landscape of disease. There remains however a huge gap in translating those data into mechanistic understanding of how genetic changes actually cause human disease. Filling this gap will require understanding of both molecules and patients. CIMR's mission is to contribute to this effort by determining the molecular mechanisms of human disease in order to develop targeted therapeutic strategies.

Located within the Cambridge Biomedical Campus, CIMR's 24 research groups are led by a mixture of clinical and non-clinical Principal Investigators. World-leading expertise in protein structure and homeostasis, membrane trafficking and organelle biology is applied across infectious, immune, neurological and haematological diseases, with a particular interest in rare genetic disorders. In several cases, these efforts are leading to new treatments and diagnostics, with several spin-out companies and drug discovery programmes established.

Dedicated core facilities at CIMR include proteomics, microscopy, bioinformatics, flow cytometry and structural biology. The Institute is also committed to diversity and inclusion, with an emphasis on a positive research culture and impactful public engagement. Postgraduate training for non-clinical and clinical students is an important part of CIMR. Our 38 PhD and two MPhil students benefit from the supportive, collaborative environment of the Institute and from the wider School of Clinical Medicine.

2 courses offered in the Cambridge Institute for Medical Research

The Cambridge Institute for Medical Research (CIMR) is one of the leading research institutions in the UK. The Institute’s mission is to determine the molecular mechanisms of disease in order to advance human health, and the institute is founded on the principle of interdisciplinarity, leveraging extensive collaboration between basic and clinician scientists, outstanding core facilities and an inclusive, supportive working environment to tackle big problems.

CIMR’s ambitious Research Strategy is to generate a detailed understanding of cellular homeostasis across three main themes: protein folding and quality control, membrane trafficking and organelle biology. These pathways are fundamental to normal cellular function, so when they are altered by mutation they can lead to diseases that are rare, devastating, and frequently occur in the nervous system. Numerous infectious pathogens have also evolved to infect cells by exploiting and manipulating these pathways. CIMR therefore focuses on genetic and infectious disease areas where cellular homeostasis is altered, and which are frequently neglected and overlooked, meaning there is significant unmet patient need: rare genetic disease, neurological disease, and intracellular infection. There are 24 research groups working across these research themes at CIMR.

A one-year full-time MPhil programme of research is offered under an individual supervision of principal investigators based in CIMR. This course can also be taken as a part-time option over two years. During their MPhil, the students are based in a research group, supported by their primary supervisor and the CIMR Postgraduate Education Committee. There is no taught and examined coursework, but students are encouraged to attend research seminars at the Cambridge Biomedical Campus and elsewhere in the University, and postgraduate student seminars dealing with generic skills such as intellectual property rights, writing a thesis or paper, and entrepreneurship. Students write a thesis, which is examined via an oral examination.

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The Cambridge Institute for Medical Research (CIMR) is one of the leading research institutions in the UK. The Institute’s mission is to determine the molecular mechanisms of disease in order to advance human health, and the institute is founded on the principle of interdisciplinarity, leveraging extensive collaboration between basic and clinician scientists, outstanding core facilities and an inclusive, supportive working environment to tackle big problems.

CIMR’s ambitious Research Strategy is to generate a detailed understanding of cellular homeostasis across three main themes: protein folding and quality control, membrane trafficking and organelle biology. These pathways are fundamental to normal cellular function, so when they are altered by mutation they can lead to diseases that are rare, devastating, and frequently occur in the nervous system. Numerous infectious pathogens have also evolved to infect cells by exploiting and manipulating these pathways. CIMR therefore focuses on genetic and infectious disease areas where cellular homeostasis is altered, and which are frequently neglected and overlooked, meaning there is significant unmet patient need: rare genetic disease, neurological disease, and intracellular infection. There are 24 research groups working across these research themes at CIMR.

A three-year full-time PhD programme of research is offered under the individual supervision of principal investigators based in CIMR. This course can also be taken as a part-time option for over six years. The PhD students are based in a research group, supported by their primary supervisor, their graduate adviser, and the CIMR Graduate Education Committee. There is no taught and examined course work, but students can take part in core topic discussion sessions held once a week by PIs in CIMR.

Along with the specific research training provided in the laboratory in which the student works, he or she receives further training within the CIMR in the form of postgraduate workshops concentrating on research techniques, research seminars both on the Cambridge Biomedical Campus and elsewhere in the University, and postgraduate student seminars dealing with generic skills such as intellectual property rights, writing a thesis or paper, and entrepreneurship. Students write a dissertation, which is examined via an oral examination.

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1 course also advertised in the Cambridge Institute for Medical Research

From the Department of Clinical Biochemistry

Awaiting Approval

Department Members


Professor Julian Rayner
Head of Department

  • 25 Academic Staff
  • 107 Postdoctoral Researchers
  • 45 Graduate Students

http://www.cimr.cam.ac.uk/

Research Areas